Revealed on Forbes, it's the world's most expensive and exclusive age-defying facial products. Most are made from expensive ingredients such as crushed pearls, caviar and exotic antioxidants extracted from rare plants like the Chilean evergreen tree. Other popular components are anti-oxidants like grape seed extract, alpha lipoic acid, chamomile oils and green tea - protectants that are said to reduce skin damage from free radicals. Among the most important ingredients are customized cell messenger proteins such as peptides and epidermal growth factor that stimulate cell growth.

Made with keratinocyte growth factor, this serum is said to turn over dead skin cells eight times faster than normal skin, plumping trouble areas like frown lines and crow's feet. Dr. Gregory Brown, RéVive's founder and president and a plastic surgeon, says he never intended to use his research on epidermal growth factor--published in 1989 in the New England Journal of Medicine--to make a skincare line. "I started making it for my mother and me, then I started giving it to patients, and then a friend of a friend was head of Neiman Marcus and suggested I started making it for the store," he says.

Available at Neiman Marcus, Saks Fifth Avenue and RÉVIVE SKINCARE

This elixir is said to fight everyday stresses and strains by stimulating the synthesis of HSP proteins with a natural extract of weeping willow. It also fights free radicals with vitamin E acetate, a natural extract of gingko biloba and marine extracts.

Available at Bergdorf Goodman, Neiman Marcus and Sisley.

Packaged on a velvet tray, this haute-couture cream comes complete with a silver spatula for application. According to the company, "La Crème gently diminishes spots, freckles and uneven tone, rebuilds elasticity and resilience, and replenishes moisture lost from the daily effects of the environment and lifestyle on skin."

Available at Bergdorf Goodman, Neiman Marcus and Saks Fifth Avenue.

After a quick swabbing of the inner lining of the cheek, the Dermagenetics lab measures genetic propensity for collagen breakdown and wrinkling. The company then makes a night cream based entirely on the custom needs of your face.

Available at select spas nationwide. For more information, visit Untitled Document.

Formulated with a 40% concentration of a bioengineered octapeptide and 10% Dermafill Complex, this Spanish product is marketed as an alternative to Botox. It "naturally augments the tissue volume, to plump up deeper wrinkles and to replenish loss of volume experienced due to aging," the company says. Piperina nigrum, an extract of black pepper, reportedly speeds up absorption.

Available at Barneys, Bergdorf Goodman, Neiman Marcus and NATURA BISSÉ - BARCELONA.

Made with a moisturizing component called bio-hyaluronate and natural extracts from apricot kernels, this cult favorite among beauty insiders promotes microcirculation, enriches the skin and aids in the elimination of fine wrinkles. The product also contains a silk fibroin derivative, a protein that reportedly holds up to 300 times its weight in water, which means it's a good moisturizer.

Available at Bergdorf Goodman, Saks Fifth Avenue and

50% pure cellular extract provides a high concentration of biological lifting and moisturizing ingredients that are said to increase the skin's oxygen absorption, stimulate cell metabolism and accelerate cellular reproductive activity.

Available at Dermalab, - Skin by Dermlab.

This serum is reported to provide both greater elasticity with iris isoflavones and firmer skin with vital essence of mamaku. Horsetail extract is said to improve skin tone, while rose extract softens.

Available at Bergdorf Goodman and Darphin : Skin care

With extracts of coneflower, sea buckthorn and rosa moschata (don't worry, we're not sure what those things are either), this haute-couture Swiss-made product is said to promote cellular exchanges, energize cell metabolism and stimulate the skin's natural defense systems.

Available at Valmont Cosmetics - Laboratoires Valmont - Recherche Valmont.

Dr. Nicholas V. Perricone, dermatologist and author of The Perricone Promise and The Wrinkle Cure, has an array of anti-aging skincare therapies, the most expensive of which contain peptides and neuropeptides--amino acids and substances released by the brain that are said to transform the skin.

Available at Neiman Marcus and N.V. Perricone, M.D. Cosmeceuticals®.

Though marketed as a "psychodermic anti-aging product," the age-defying capabilities of this cream seem to come from a rather obscure ingredient: red tocol arctic cranberry, which is said to have a high concentration of Omego-3 fatty acids.

Available at Neiman Marcus.

AmorePacific has isolated and stabilized EGCF--the most vital ingredient in green tea--and adapted it for skincare. The company even cultivates its own green tea at the foot of Halla Mountain on Iush Jeju Island off the coast of Korea. Other key ingredients include a form of red ginseng that is purported to stimulate collagen synthesis.

Available at Bergdorf Goodman.

Sérénissima has Guerlain's patented ingredient, H-Captine Complex, which is meant to hydrate and replenish skin. Ginko biloba is also added to preserve the skin's elasticity.

Available at Bergdorf Goodman, select Bloomingdales, Neiman Marcus, Saks Fifth Avenue and Guerlain Paris : beauty care for the body, women fragrance and men fragrance.

With fifty-four ingredients from around the world--including a powder of crushed South Sea pearls that is said to even skin tone--Estée Lauder's Re-Nutriv Ultimate Lifting Eye Crème is said to even skin tone and radiance. Moisture magnet hyaluronic acid also plumps the skin, thereby diminishing the appearance of fine wrinkles.

Available at Bergdorf Goodman, Bloomingdale's, Neiman Marcus, Saks Fifth Avenue and Estée Lauder | Official Site for Estée Lauder Skincare, Makeup and Fragrance Products.